Blocked angiogenesis in Galectin-3 null mice does not alter cellular and behavioral recovery after middle cerebral artery occlusion stroke

Blocked angiogenesis in Galectin-3 null mice does not alter cellular and behavioral recovery after middle cerebral artery occlusion stroke

Angiogenesis is thought to decrease stroke size and improve behavioral outcomes and therefore several clinical trials are seeking to augment it. Galectin-3 (Gal-3) expression increases after middle cerebral artery occlusion (MCAO) and has been proposed to limit damage 3 days after stroke. We carried...

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Bibliographic Details
Main Authors: Christopher C. Young, Osama Al-Dalahmah, Nicola J. Lewis, Keith J. Brooks, Micaela M. Jenkins, Françoise Poirier, Alastair M. Buchan, Francis G. Szele
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Neurobiology of Disease
Subjects:
Angiogenesis
Ischemia
Middle cerebral artery occlusion
Migration
Neurogenesis
Neural repair
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611300315X

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http://www.sciencedirect.com/science/article/pii/S096999611300315X

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