The Addition of High Doses of Hyaluronic Acid to a Biphasic Bone Substitute Decreases the Proinflammatory Tissue Response

The Addition of High Doses of Hyaluronic Acid to a Biphasic Bone Substitute Decreases the Proinflammatory Tissue Response

Biphasic bone substitutes (BBS) are currently well-established biomaterials. Through their constant development, even natural components like hyaluronic acid (HY) have been added to improve both their handling and also their regenerative properties. However, little knowledge exists regarding the con...

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Bibliographic Details
Main Authors: Dominik Sieger, Tadas Korzinskas, Ole Jung, Sanja Stojanovic, Sabine Wenisch, Ralf Smeets, Martin Gosau, Reinhard Schnettler, Stevo Najman, Mike Barbeck
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
hyaluronic acid
biphasic bone substitute
biocompatibility
tissue reaction
inflammation
macrophage
M1
M2
multinucleated giant cells
Online Access:https://www.mdpi.com/1422-0067/20/8/1969

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https://www.mdpi.com/1422-0067/20/8/1969

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