BALAYAN PARADOX

• Main Authors: M. I. Mikhailov, E. Yu. Malinnikova, K. K. Kyuregyan, I. A. Potemkin, N. D. Alsalikh, O. V. Isaeva, A. A. Karlsen, V. S. Kichatova, A. D. Polyakov
• Format: Article
• Language: Russian
• Published: Central Research Institute for Epidemiology 2019-08-01
• Series: Журнал микробиологии, эпидемиологии и иммунобиологии
• Subjects: hepatitis е; hepatitic е virus; antibodies; transmission; zoonosis
• Online Access: https://microbiol.elpub.ru/jour/article/view/386

This article presents the results of a study of the epidemiology of hepatitis E in the Russian Federation. Obtained data explaining the phenomenon, known as the Balayan paradox — the wide distribution of anamnestic antibodies to the hepatitis E virus in the absence of a registered incidence. It was shown that imported cases of infection are not able to support the epidemiological process of hepatitis E in Russia. The most cases of HEV infection are autochthonous in nature and are associated with zoonotic transmission of genotype 3 virus from pigs.