The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists

Nearly 1% of all clinically used drugs are catecholics, a family of catechol-containing compounds. Using label-free dynamic mass redistribution and Tango β-arrestin translocation assays, we show that several catecholics, including benserazide, catechol, 3-methoxycatechol, pyrogallol, (+)-taxifolin a...

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Bibliographic Details
Main Authors: Huayun Deng, Ye Fang
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/6/4/500