ROS-Induced JNK and p38 Signaling Is Required for Unpaired Cytokine Activation during Drosophila Regeneration.

Upon apoptotic stimuli, epithelial cells compensate the gaps left by dead cells by activating proliferation. This has led to the proposal that dying cells signal to surrounding living cells to maintain homeostasis. Although the nature of these signals is not clear, reactive oxygen species (ROS) coul...

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Bibliographic Details
Main Authors: Paula Santabárbara-Ruiz, Mireya López-Santillán, Irene Martínez-Rodríguez, Anahí Binagui-Casas, Lídia Pérez, Marco Milán, Montserrat Corominas, Florenci Serras
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4619769?pdf=render