Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012
Knowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010–March 2012, rotavirus surveillance was conducted among 9,745 children <5 years of age in 14 hospitals/health centers in Niger, where rotavirus v...
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doaj-c9c8d3f231ce4d5591cf1ba44db643da2020-11-25T01:05:22ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-04-0120457358010.3201/eid2004.131328Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012Anne-Laure PageViviane JusotAbdoul-Aziz MamatyLagare AdamouJérôme KaplonPierre PothierAli DjiboMahamane L. ManzoBrahima ToureCéline LangendorfJean-Marc CollardRebecca F. GraisKnowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010–March 2012, rotavirus surveillance was conducted among 9,745 children <5 years of age in 14 hospitals/health centers in Niger, where rotavirus vaccine has not been introduced. Study participants had acute watery diarrhea and moderate to severe dehydration, and 20% of the children were enrolled in a nutrition program. Of the 9,745 children, 30.6% were rotavirus positive. Genotyping of a subset of positive samples showed a variety of genotypes during the first year, although G2P[4] predominated. G12 genotypes, including G12P[8], which has emerged as a predominant strain in western Africa, represented >80% of isolates during the second year. Hospitalization and death rates and severe dehydration among rotavirus case-patients did not differ during the 2 years. The emergence of G12P[8] warrants close attention to the characteristics of associated epidemics and possible prevention measures.https://wwwnc.cdc.gov/eid/article/20/4/13-1328_articlerotavirusgenotypingdiarrheal diseasesNigerdeveloping countriesmalnutrition |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anne-Laure Page Viviane Jusot Abdoul-Aziz Mamaty Lagare Adamou Jérôme Kaplon Pierre Pothier Ali Djibo Mahamane L. Manzo Brahima Toure Céline Langendorf Jean-Marc Collard Rebecca F. Grais |
spellingShingle |
Anne-Laure Page Viviane Jusot Abdoul-Aziz Mamaty Lagare Adamou Jérôme Kaplon Pierre Pothier Ali Djibo Mahamane L. Manzo Brahima Toure Céline Langendorf Jean-Marc Collard Rebecca F. Grais Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012 Emerging Infectious Diseases rotavirus genotyping diarrheal diseases Niger developing countries malnutrition |
author_facet |
Anne-Laure Page Viviane Jusot Abdoul-Aziz Mamaty Lagare Adamou Jérôme Kaplon Pierre Pothier Ali Djibo Mahamane L. Manzo Brahima Toure Céline Langendorf Jean-Marc Collard Rebecca F. Grais |
author_sort |
Anne-Laure Page |
title |
Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012 |
title_short |
Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012 |
title_full |
Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012 |
title_fullStr |
Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012 |
title_full_unstemmed |
Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012 |
title_sort |
rotavirus surveillance in urban and rural areas of niger, april 2010–march 2012 |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2014-04-01 |
description |
Knowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010–March 2012, rotavirus surveillance was conducted among 9,745 children <5 years of age in 14 hospitals/health centers in Niger, where rotavirus vaccine has not been introduced. Study participants had acute watery diarrhea and moderate to severe dehydration, and 20% of the children were enrolled in a nutrition program. Of the 9,745 children, 30.6% were rotavirus positive. Genotyping of a subset of positive samples showed a variety of genotypes during the first year, although G2P[4] predominated. G12 genotypes, including G12P[8], which has emerged as a predominant strain in western Africa, represented >80% of isolates during the second year. Hospitalization and death rates and severe dehydration among rotavirus case-patients did not differ during the 2 years. The emergence of G12P[8] warrants close attention to the characteristics of associated epidemics and possible prevention measures. |
topic |
rotavirus genotyping diarrheal diseases Niger developing countries malnutrition |
url |
https://wwwnc.cdc.gov/eid/article/20/4/13-1328_article |
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