Melatonin postconditioning combined with sitagliptin exerts full cardioprotection in diabetic hearts of aged rats through an AMPK-dependent mechanism

Melatonin postconditioning combined with sitagliptin exerts full cardioprotection in diabetic hearts of aged rats through an AMPK-dependent mechanism

The presence of multiple comorbidities in patients facing myocardial ischemia-reperfusion (IR) injury is the main obstacle for cardioprotection. This study investigated the effect of melatonin postconditioning combined with sitagliptin pretreatment on cardioprotection in diabetic aged rats by evalua...

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Bibliographic Details
Main Authors: Song Ronggang, Ren Jing, Sun Junxia, Li Ming
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2021-01-01
Series:Archives of Biological Sciences
Subjects:
diabetes
cardioprotection
aging
ampk
postconditioning
melatonin
dpp-4
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2021/0354-46642100004S.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2021/0354-46642100004S.pdf

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