Amino acid permeases in Cryptococcus neoformans are required for high temperature growth and virulence; and are regulated by Ras signaling.

Amino acid permeases in Cryptococcus neoformans are required for high temperature growth and virulence; and are regulated by Ras signaling.

Cryptococcosis is an Invasive Fungal Infection (IFI) caused by Cryptococcus neoformans, mainly in immunocompromised patients. Therapeutic failure due to pathogen drug resistance, treatment inconstancy and few antifungal options is a problem. The study of amino acid biosynthesis and uptake represents...

Full description

Bibliographic Details
Main Authors: Crislaine Lambiase Calvete, Kevin Felipe Martho, Gabrielle Felizardo, Alexandre Paes, João Miguel Nunes, Camila Oliveira Ferreira, Marcelo A Vallim, Renata C Pascon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211393

Internet

https://doi.org/10.1371/journal.pone.0211393

Similar Items