Clinical Features and Quality of Life in End Stage Renal Disease Patients Undergoing Hemodialysis Twice A Week Compared to Thrice A Week

Introduction. National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NFK-KDOQI) recommends thrice weekly hemodialysis (HD) However, in Indonesia, most patients are given HD twice a week. Therefore it is necessary to investigate the clinical features and quality of life in End Stage R...

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Main Authors: Fitri Imelda, Endang Susalit, Maruhum Bonar M Marbun, Cleopas Martin Rumende
Format: Article
Language:Indonesian
Published: Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital 2017-09-01
Series:Jurnal Penyakit Dalam Indonesia
Subjects:
Online Access:http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/139/125
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spelling doaj-cae4e722eee94155873ece2f9a8a69492020-11-25T00:57:17ZindDepartment of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo HospitalJurnal Penyakit Dalam Indonesia2406-89692549-06212017-09-0143128136http://dx.doi.org/10.7454/jpdi.v4i3.139Clinical Features and Quality of Life in End Stage Renal Disease Patients Undergoing Hemodialysis Twice A Week Compared to Thrice A WeekFitri Imelda0Endang Susalit1Maruhum Bonar M Marbun2Cleopas Martin Rumende3Divisi Ginjal Hipertensi, Departemen Ilmu Penyakit Dalam, FKUI/RSCM Indonesia Divisi Ginjal Hipertensi, Departemen Ilmu Penyakit Dalam, FKUI/RSCM Indonesia Divisi Ginjal Hipertensi, Departemen Ilmu Penyakit Dalam, FKUI/RSCM Indonesia Cleopas Martin RumendeIntroduction. National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NFK-KDOQI) recommends thrice weekly hemodialysis (HD) However, in Indonesia, most patients are given HD twice a week. Therefore it is necessary to investigate the clinical features and quality of life in End Stage Renal Disease (ESRD) patients undergoing twice-weekly HD. This study aimed to identify the clinical features and the quality of life in ESRD patients undergoing hemodialysis twice a week. Methods. A cross-sectional study was conducted in ESRD patients undergoing twice-weekly HD and thrice-weekly HD at Cipto Mangunkusumo Hospital and some private hospitals in Jakarta. Blood samples were obtained for laboratory examination. Meanwhile, quality of life were assessed by using Kidney Disease Quality of Life (KDQOL-SF 36). Results. A total of 80 subjects were included in this study, most of them were male and over 50 years old. Some clinical features were significantly higher in twice-weekly HD patients compared to thrice-weekly HD patients. Those features were Interdialytic Weight Gain (IDWG) (mean 4.91% (SD 1.52) and 3.82% (SD 1.28); p= 0.002); albumin (mean 4.05 mg/dl (SD 0.26) and 3.86 mg/dl (SD 0.48); p= 0.027); transferrin saturation (median 25.5% (range 12.0 to 274.0) and 21.95% (5.8 to 84.2); p= 0.004); phosphate level (mean 5.82 mg/dl (SD 1.68) and 5.82 mg/dl (SD 1.68); p= 0.026. Meanwhile, Total Iron Binding Capacity (TIBC) was significantly higher in thrice-weekly HD patients (mean 235.20 μg/dl (SD 55.72) and 273.73 μg/dl (SD 58.29 SB); p= 0.004). Approximately, 68% of twice-weekly HD reached Kt/V >1.8 and 93.3% of thrice-weekly HD reached Kt/V >1.2. Quality of life between the two groups was not significant either on Physical Componet Score (PCS) (p= 0.227), Mental Component Score (MCS) (p= 0.247), and Kidney Disease Component Score (KDCS) (p= 0.889). Conclusions. There are statistically significant differences between clinical features of twice-weekly HD and thrice-weekly HD on examination of IDWG, albumin, transferrin saturation, and phosphate levels which are higher in twice-weekly HD. Whereas, TIBC is higher in thrice-weekly HD group. Meanwhile, the patients quality of life in both groups showed no statistically significant differences.http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/139/125ESRDhemodialysis frequencyquality of life
collection DOAJ
language Indonesian
format Article
sources DOAJ
author Fitri Imelda
Endang Susalit
Maruhum Bonar M Marbun
Cleopas Martin Rumende
spellingShingle Fitri Imelda
Endang Susalit
Maruhum Bonar M Marbun
Cleopas Martin Rumende
Clinical Features and Quality of Life in End Stage Renal Disease Patients Undergoing Hemodialysis Twice A Week Compared to Thrice A Week
Jurnal Penyakit Dalam Indonesia
ESRD
hemodialysis frequency
quality of life
author_facet Fitri Imelda
Endang Susalit
Maruhum Bonar M Marbun
Cleopas Martin Rumende
author_sort Fitri Imelda
title Clinical Features and Quality of Life in End Stage Renal Disease Patients Undergoing Hemodialysis Twice A Week Compared to Thrice A Week
title_short Clinical Features and Quality of Life in End Stage Renal Disease Patients Undergoing Hemodialysis Twice A Week Compared to Thrice A Week
title_full Clinical Features and Quality of Life in End Stage Renal Disease Patients Undergoing Hemodialysis Twice A Week Compared to Thrice A Week
title_fullStr Clinical Features and Quality of Life in End Stage Renal Disease Patients Undergoing Hemodialysis Twice A Week Compared to Thrice A Week
title_full_unstemmed Clinical Features and Quality of Life in End Stage Renal Disease Patients Undergoing Hemodialysis Twice A Week Compared to Thrice A Week
title_sort clinical features and quality of life in end stage renal disease patients undergoing hemodialysis twice a week compared to thrice a week
publisher Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital
series Jurnal Penyakit Dalam Indonesia
issn 2406-8969
2549-0621
publishDate 2017-09-01
description Introduction. National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NFK-KDOQI) recommends thrice weekly hemodialysis (HD) However, in Indonesia, most patients are given HD twice a week. Therefore it is necessary to investigate the clinical features and quality of life in End Stage Renal Disease (ESRD) patients undergoing twice-weekly HD. This study aimed to identify the clinical features and the quality of life in ESRD patients undergoing hemodialysis twice a week. Methods. A cross-sectional study was conducted in ESRD patients undergoing twice-weekly HD and thrice-weekly HD at Cipto Mangunkusumo Hospital and some private hospitals in Jakarta. Blood samples were obtained for laboratory examination. Meanwhile, quality of life were assessed by using Kidney Disease Quality of Life (KDQOL-SF 36). Results. A total of 80 subjects were included in this study, most of them were male and over 50 years old. Some clinical features were significantly higher in twice-weekly HD patients compared to thrice-weekly HD patients. Those features were Interdialytic Weight Gain (IDWG) (mean 4.91% (SD 1.52) and 3.82% (SD 1.28); p= 0.002); albumin (mean 4.05 mg/dl (SD 0.26) and 3.86 mg/dl (SD 0.48); p= 0.027); transferrin saturation (median 25.5% (range 12.0 to 274.0) and 21.95% (5.8 to 84.2); p= 0.004); phosphate level (mean 5.82 mg/dl (SD 1.68) and 5.82 mg/dl (SD 1.68); p= 0.026. Meanwhile, Total Iron Binding Capacity (TIBC) was significantly higher in thrice-weekly HD patients (mean 235.20 μg/dl (SD 55.72) and 273.73 μg/dl (SD 58.29 SB); p= 0.004). Approximately, 68% of twice-weekly HD reached Kt/V >1.8 and 93.3% of thrice-weekly HD reached Kt/V >1.2. Quality of life between the two groups was not significant either on Physical Componet Score (PCS) (p= 0.227), Mental Component Score (MCS) (p= 0.247), and Kidney Disease Component Score (KDCS) (p= 0.889). Conclusions. There are statistically significant differences between clinical features of twice-weekly HD and thrice-weekly HD on examination of IDWG, albumin, transferrin saturation, and phosphate levels which are higher in twice-weekly HD. Whereas, TIBC is higher in thrice-weekly HD group. Meanwhile, the patients quality of life in both groups showed no statistically significant differences.
topic ESRD
hemodialysis frequency
quality of life
url http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/139/125
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