The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study.

Sepsis-associated encephalopathy (SAE) contributes to mortality and neurocognitive impairment of sepsis patients. Neurofilament (Nf) light (NfL) and heavy (NfH) chain levels as biomarkers for neuroaxonal injury were not evaluated in cerebrospinal fluid (CSF) and plasma of patients with sepsis-associ...

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Main Authors: Johannes Ehler, Axel Petzold, Matthias Wittstock, Stephan Kolbaske, Martin Gloger, Jörg Henschel, Amanda Heslegrave, Henrik Zetterberg, Michael P Lunn, Paulus S Rommer, Annette Grossmann, Tarek Sharshar, Georg Richter, Gabriele Nöldge-Schomburg, Martin Sauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211184