The synthesis and pharmacological evaluation of (±)-2,3-seco-fentanyl analogues

The synthesis and pharmacological evaluation of (±)-2,3-seco-fentanyl analogues

An efficient, five-step synthetic approach to various acyclic 1,3-diamines has been developed and applied to the preparation of a novel class of open-chained fentanyl analogues. The acyclic derivatives 5.15.5 (all new compounds) were synthesized with the aim of estimating the significance of the pip...

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Bibliographic Details
Main Authors: LJ. DOSEN-MICOVIC, J. B. DJORDJEVIC, V. D. KIRICOJEVIC, E. R. IVANOVIC, Z. TODOROVIC, M. PROSTRAN, S. VUCKOVIC, I. V. MICOVIC, M. D. IVANOVIC
Format: Article
Language:English
Published: Serbian Chemical Society 2004-11-01
Series:Journal of the Serbian Chemical Society
Subjects:
open-chain fentanyl analogues
1
3-diamines
opioid analgesics
Online Access:http://www.shd.org.yu/HtDocs/SHD/Vol69/No11/V69-No11-15.pdf

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http://www.shd.org.yu/HtDocs/SHD/Vol69/No11/V69-No11-15.pdf

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