SDF-1α/MicroRNA-134 Axis Regulates Nonfunctioning Pituitary Neuroendocrine Tumor Growth via Targeting VEGFA

SDF-1α/MicroRNA-134 Axis Regulates Nonfunctioning Pituitary Neuroendocrine Tumor Growth via Targeting VEGFA

BackgroundNonfunctioning pituitary neuroendocrine tumor (NF-PitNET) is difficult to resect. Except for surgery, there is no effective treatment for NF-PitNET. MicroRNA-134 (miR-134) has been reported to inhibit proliferation and invasion ability of tumor cells. Herein, the mechanism underlying the e...

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Bibliographic Details
Main Authors: Xiaoyu Wang, Yuanjian Fang, Yunxiang Zhou, Xiaoming Guo, Ke Xu, Chenguang Li, Jianmin Zhang, Yuan Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Endocrinology
Subjects:
SDF-1α (CXCL12)
vascular endothelial growth factor A (VEGFA)
proliferation
invasion
microRNA-134(miR-134)
nonfunctioning pituitary neuroendocrine tumor (NF-PitNET)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.566761/full

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https://www.frontiersin.org/articles/10.3389/fendo.2020.566761/full

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