Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study

Background: The clinical and pathologic diversity of systemic lupus erythematosus (SLE) hinders diagnosis, management, and treatment development. This study addresses heterogeneity in SLE through comprehensive molecular phenotyping and machine learning clustering. Methods: Adult SLE patients (n = 19...

Full description

Bibliographic Details
Main Authors: Joel M. Guthridge, Rufei Lu, Ly Thi-Hai Tran, Cristina Arriens, Teresa Aberle, Stan Kamp, Melissa E. Munroe, Nicolas Dominguez, Timothy Gross, Wade DeJager, Susan R. Macwana, Rebecka L. Bourn, Stephen Apel, Aikaterini Thanou, Hua Chen, Eliza F. Chakravarty, Joan T. Merrill, Judith A. James
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537020300353