Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.

BACKGROUND:Up until recently the only available experimental (high resolution) structure of a G-protein-coupled receptor (GPCR) was that of bovine rhodopsin. In the past few years the determination of GPCR structures has accelerated with three new receptors, as well as squid rhodopsin, being success...

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Bibliographic Details
Main Authors: Catherine L Worth, Gunnar Kleinau, Gerd Krause
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2738427?pdf=render