The role of local renin-angiotensin system on high glucose-induced cell toxicity, apoptosis and reactive oxygen species production in PC12 cells

The role of local renin-angiotensin system on high glucose-induced cell toxicity, apoptosis and reactive oxygen species production in PC12 cells

Objective(s): Hyperglycemia, oxidative stress and apoptosis have key roles in pathogenesis of diabetic neuropathy. There are local renin-angiotensin systems (RASs) in different tissues such as neural tissue. Local RASs are involved in physiological and pathophysiological processes such as inflammati...

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Main Authors: Kaveh Shahveisi, Seyed Hadi Mousavi, Mahmoud Hosseini, Abolfazl Khajavi Rad, Seyed Amir Jalali, Ziba Rajaei, Hamid Reza Sadeghnia, Mousa-Al-Reza Hadjzadeh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2014-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Apoptosis High glucose toxicity Oxidative stress PC12 Renin-angiotensin system
Online Access:http://ijbms.mums.ac.ir/pdf_3196_e5c95ba36c6297a635c9097c621a6f20.html

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http://ijbms.mums.ac.ir/pdf_3196_e5c95ba36c6297a635c9097c621a6f20.html

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