Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data.

<h4>Background</h4>The surveillance of drug resistance among tuberculosis (TB) patients is central to combatting the global TB epidemic and preventing the spread of antimicrobial resistance. Isoniazid and rifampicin are two of the most powerful first-line anti-TB medicines, and resistanc...

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Main Authors: Anna S Dean, Matteo Zignol, Andrea Maurizio Cabibbe, Dennis Falzon, Philippe Glaziou, Daniela Maria Cirillo, Claudio U Köser, Lice Y Gonzalez-Angulo, Olga Tosas-Auget, Nazir Ismail, Sabira Tahseen, Maria Cecilia G Ama, Alena Skrahina, Natavan Alikhanova, S M Mostofa Kamal, Katherine Floyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003008