Prediction of Escherichia coli expression performance in microtiter plates by analyzing only the temporal development of scattered light during culture

Abstract Background Escherichia coli is often used for recombinant protein production. The expression of recombinant proteins negatively affects the microbial growth, thus, a balance between protein expression and biomass formation is preferable to reach high product- and space-time-yield. Already i...

Full description

Bibliographic Details
Main Authors: Tobias Ladner, Martina Mühlmann, Andreas Schulte, Georg Wandrey, Jochen Büchs
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Biological Engineering
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13036-017-0064-5