Determination of ionization constants (PKA) of β-hydroxy-β-arylalkanoic acids using high-pressure liquid chromatography
pKa values of five β-hydroxy-β-arylalkanoic acids and ibuprofen were determined using the RP-HPLC method. Stationary phase was octadecyl modified (C-18) silica gel, and mobile phase was a mixture of methanol and one of nine different buffers (60:40, v/v). wspH values were measured after mixing metha...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
University of Kragujevac, Faculty of Science
2018-01-01
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Series: | Kragujevac Journal of Science |
Subjects: | |
Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1450-9636/2018/1450-96361840103S.pdf |