Rapid Identification of Mutations in Quinolone-Resistant Shigella Isolates by Scanning of gyrA and parC Genes using High-Resolution Melting Curve Analysis

Rapid Identification of Mutations in Quinolone-Resistant Shigella Isolates by Scanning of gyrA and parC Genes using High-Resolution Melting Curve Analysis

Objectives: Mutations in the quinolone resistance–determining regions (QRDRs) of the topoisomerase genes are considered to be a primary mechanism of quinolone and fluoroquinolone resistance. The objective of this study was to identify the most common gyrA and parC mutations in Shigella spp., with th...

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Bibliographic Details
Main Authors: Mohammad Mehdi Soltan Dallal, Sajad Yaghoubi, Asiyeh Dezhkam, Shahriyar Yavari, Azad Jamee
Format: Article
Language:English
Published: Light House Polyclinic Mangalore 2020-05-01
Series:Online Journal of Health & Allied Sciences
Subjects:
shigellosis
dna gyrase
topoisomerase iv
high-resolution melting
Online Access:https://www.ojhas.org/issue73/2020-1-4.html

Internet

https://www.ojhas.org/issue73/2020-1-4.html

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