High Content Image Based Analysis Identifies Cell Cycle Inhibitors as Regulators of Ebola Virus Infection

High Content Image Based Analysis Identifies Cell Cycle Inhibitors as Regulators of Ebola Virus Infection

Viruses modulate a number of host biological responses including the cell cycle to favor their replication. In this study, we developed a high-content imaging (HCI) assay to measure DNA content and identify different phases of the cell cycle. We then investigated the potential effects of cell cycle...

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Bibliographic Details
Main Authors: Sina Bavari, Rekha G. Panchal, Julie P. Tran, Rajini Mudhasani, Cary Retterer, Jacqueline G. Benko, Krishna P. Kota
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Viruses
Subjects:
ebolavirus
cell cycle
high-content imaging
serum starvation
aphidicolin
nocodazole
Online Access:http://www.mdpi.com/1999-4915/4/10/1865

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