Effects of radiation damage and inelastic scattering on single-particle imaging of hydrated proteins with an X-ray Free-Electron Laser

Abstract We present a computational case study of X-ray single-particle imaging of hydrated proteins on an example of 2-Nitrogenase–Iron protein covered with water layers of various thickness, using a start-to-end simulation platform and experimental parameters of the SPB/SFX instrument at the Europ...

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Bibliographic Details
Main Authors: Juncheng E, Michal Stransky, Zoltan Jurek, Carsten Fortmann-Grote, Libor Juha, Robin Santra, Beata Ziaja, Adrian P. Mancuso
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97142-5