miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA

miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA

During brain wiring, cue-induced axon behaviors such as directional steering and branching are aided by localized mRNA translation. Different guidance cues elicit translation of subsets of mRNAs that differentially regulate the cytoskeleton, yet little is understood about how specific mRNAs are sele...

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Bibliographic Details
Main Authors: Anaïs Bellon, Archana Iyer, Simone Bridi, Flora C.Y. Lee, Cesaré Ovando-Vázquez, Eloina Corradi, Sara Longhi, Michela Roccuzzo, Stephanie Strohbuecker, Sindhu Naik, Peter Sarkies, Eric Miska, Cei Abreu-Goodger, Christine E. Holt, Marie-Laure Baudet
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Cell Reports
Subjects:
miRNAs
local translation
growth cone
axon guidance
brain wiring
miR-182
Slit2
cofilin
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717300037

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http://www.sciencedirect.com/science/article/pii/S2211124717300037

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