Multiplicity and molecular epidemiology of Plasmodium vivax and Plasmodium falciparum infections in East Africa

Multiplicity and molecular epidemiology of Plasmodium vivax and Plasmodium falciparum infections in East Africa

Abstract Background Parasite genetic diversity and multiplicity of infection (MOI) affect clinical outcomes, response to drug treatment and naturally-acquired or vaccine-induced immunity. Traditional methods often underestimate the frequency and diversity of multiclonal infections due to technical s...

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Bibliographic Details
Main Authors: Daibin Zhong, Eugenia Lo, Xiaoming Wang, Delenasaw Yewhalaw, Guofa Zhou, Harrysone E. Atieli, Andrew Githeko, Elizabeth Hemming-Schroeder, Ming-Chieh Lee, Yaw Afrane, Guiyun Yan
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Malaria Journal
Subjects:
Multiplicity of infection
Merozoite surface protein 1
Amplicon deep sequencing
Molecular epidemiology
Plasmodium
Within-host diversity
Online Access:http://link.springer.com/article/10.1186/s12936-018-2337-y

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http://link.springer.com/article/10.1186/s12936-018-2337-y

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