RECOMBINANT POLYPEPTIDES BASED ON C5A PEPTIDASE AS POTENTIAL VACCINE COMPONENTS AGAINST GROUP B STREPTOCOCCI

Аbstract. Gene fragments encoding N-terminal and central parts of group B streptococci (GBS) C5a peptidase were cloned in E. coli M15. The appropriate recombinant SCPB1a and SCPB3a polypeptides with molecular masses of, resp., 12.0±0.5 kDa and 11.0±0.5 kDa, were subject to expression and affinity pu...

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Bibliographic Details
Main Authors: N. V. Duplik, I. V. Koroleva, K. B. Grabovskaya, A. N. Suvorov
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/281