Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis.

Multiple sclerosis (MS) is a complex disease of the central nervous system of unknown etiology. The human leukocyte antigen (HLA) locus on chromosome 6 confers a considerable part of the susceptibility to MS, and the most important factor is the class II allele HLA-DRB1*15:01. In addition, we and ot...

Full description

Bibliographic Details
Main Authors: Jenny Link, Ingrid Kockum, Aslaug R Lorentzen, Benedicte A Lie, Elisabeth G Celius, Helga Westerlind, Marie Schaffer, Lars Alfredsson, Tomas Olsson, Boel Brynedal, Hanne F Harbo, Jan Hillert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22586495/pdf/?tool=EBI