Interactions between species introduce spurious associations in microbiome studies.

Microbiota contribute to many dimensions of host phenotype, including disease. To link specific microbes to specific phenotypes, microbiome-wide association studies compare microbial abundances between two groups of samples. Abundance differences, however, reflect not only direct associations with t...

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Bibliographic Details
Main Authors: Rajita Menon, Vivek Ramanan, Kirill S Korolev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5786326?pdf=render