Immunoregulatory Effects of Mesenchymal Stem Cell-Derived Extracellular Vesicles on T Lymphocytes

The immunomodulatory activity of mesenchymal stem cells (MSCs) is largely mediated by paracrine factors. We have recently shown that the immunosuppressive effects of MSCs on B lymphocytes in peripheral blood mononuclear cell (PBMC) culture can be reproduced by extracellular vesicles (EVs) isolated f...

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Bibliographic Details
Main Authors: Andrea Del Fattore, Rosa Luciano, Luisa Pascucci, Bianca Maria Goffredo, Ezio Giorda, Margherita Scapaticci, Alessandra Fierabracci, Maurizio Muraca M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2015-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X687543