Upregulation of interleukin-19 in severe asthma: a potential saliva biomarker for asthma severity

Upregulation of interleukin-19 in severe asthma: a potential saliva biomarker for asthma severity

Interleukin (IL)-19, a designated IL-20 subfamily cytokine, has been implicated in inflammatory disorders including rheumatoid arthritis, psoriasis and, lately, asthma. Here, through the analysis of transcriptomic datasets of lung tissue of large asthma cohorts, we report that IL-19 expression is up...

Full description

Bibliographic Details
Main Authors:	Fatemeh Saheb Sharif-Askari, Narjes Saheb Sharif-Askari, Swati Goel, Bassam Mahboub, Abdul Wahid Ansari, Mohamad-Hani Temsah, Adel M. Zakri, Elaref Ratemi, Rifat Hamoudi, Qutayba Hamid, Rabih Halwani
Format:	Article
Language:	English
Published:	European Respiratory Society 2021-07-01
Series:	ERJ Open Research
Online Access:	http://openres.ersjournals.com/content/7/3/00984-2020.full

Similar Items

Association between body mass index and asthma severity in Arab pediatric population: A retrospective study.
by: Narjes Saheb Sharif-Askari, et al.
Published: (2019-01-01)

SARS-CoV-2 Switches ‘on’ MAPK and NFκB Signaling via the Reduction of Nuclear DUSP1 and DUSP5 Expression
by: Swati Goel, et al.
Published: (2021-04-01)

Cardiovascular medications and regulation of COVID-19 receptors expression
by: Narjes Saheb Sharif-Askari, et al.
Published: (2020-09-01)

Airways Expression of SARS-CoV-2 Receptor, ACE2, and TMPRSS2 Is Lower in Children Than Adults and Increases with Smoking and COPD
by: Narjes Saheb Sharif-Askari, et al.
Published: (2020-09-01)

Enhanced Expression of Autoantigens During SARS-CoV-2 Viral Infection
by: Narjes Saheb Sharif-Askari, et al.
Published: (2021-06-01)

Azithromycin Differentially Alters TCR-Activated Helper T Cell Subset Phenotype and Effector Function
by: Abdul Wahid Ansari, et al.
Published: (2020-09-01)

Enhanced expression of immune checkpoint receptors during SARS-CoV-2 viral infection
by: Narjes Saheb Sharif-Askari, et al.
Published: (2021-03-01)

Blood and Salivary Amphiregulin Levels as Biomarkers for Asthma
by: Mahmood Yaseen Hachim, et al.
Published: (2020-10-01)

Low Vitamin D Serum Level Is Associated with HDL-C Dyslipidemia and Increased Serum Thrombomodulin Levels of Insulin-Resistant Individuals
by: Saheb Sharif-Askari F, et al.
Published: (2020-05-01)

Asthma severity as a contributing factor to cancer incidence: A cohort study.
by: Laila Salameh, et al.
Published: (2021-01-01)

Three common single-nucleotide variants in the promoter region of thymic stromal lymphopoietin cytokine are not associated with asthma prevalence in a Saudi Arabian population
by: Maha Fahad Alenazy, et al.
Published: (2020-01-01)

Adverse drug reactions reported to the drug and poison information center of Tehran, Iran.
by: Fatemeh Saheb Sharif-Askari, et al.
Published: (2017-01-01)

Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients.
by: Rakhee K Ramakrishnan, et al.
Published: (2020-01-01)

Logistic regression prediction model identify type 2 diabetes mellitus as a prognostic factor for human papillomavirus-16 associated head and neck squamous cell carcinoma.
by: Aastha Sobti, et al.
Published: (2019-01-01)

Development of an adverse drug reaction risk assessment score among hospitalized patients with chronic kidney disease.
by: Fatemeh Saheb Sharif-Askari, et al.
Published: (2014-01-01)

SARS-CoV-2 Infection-Induced Promoter Hypomethylation as an Epigenetic Modulator of Heat Shock Protein A1L (HSPA1L) Gene
by: Jibran Sualeh Muhammad, et al.
Published: (2021-02-01)

The psychological impact of the COVID-19 pandemic on adults and children in the United Arab Emirates: a nationwide cross-sectional study
by: Basema Saddik, et al.
Published: (2021-05-01)

Is it severe asthma or asthma with severe comorbidities?
by: Brussino L, et al.
Published: (2017-11-01)

Systems Immunology Analysis Reveals the Contribution of Pulmonary and Extrapulmonary Tissues to the Immunopathogenesis of Severe COVID-19 Patients
by: Sarah Musa Hammoudeh, et al.
Published: (2021-06-01)

Adverse outcomes of anticoagulant use among hospitalized patients with chronic kidney disease: a comparison of the rates of major bleeding events between unfractionated heparin and enoxaparin.
by: Fatemeh Saheb Sharif-Askari, et al.
Published: (2014-01-01)

Nucleic Acid-Sensing Pathways During SARS-CoV-2 Infection: Expectations versus Reality
by: Mdkhana B, et al.
Published: (2021-01-01)

IL-17 Induced Autophagy Regulates Mitochondrial Dysfunction and Fibrosis in Severe Asthmatic Bronchial Fibroblasts
by: Rakhee K. Ramakrishnan, et al.
Published: (2020-05-01)

Airway Microbiota in Severe Asthma and Relationship to Asthma Severity and Phenotypes.
by: Qingling Zhang, et al.
Published: (2016-01-01)

The Molecular Basis of Gender Variations in Mortality Rates Associated With the Novel Coronavirus (COVID-19) Outbreak
by: Ibrahim Y. Hachim, et al.
Published: (2021-09-01)

Incidence and Clinicopathological Features of Breast Cancer in the Northern Emirates: Experience from Sharjah Breast Care Center
by: Bendardaf R, et al.
Published: (2020-10-01)

Omalizumab for Severe Asthma: Beyond Allergic Asthma
by: C. C. Loureiro, et al.
Published: (2018-01-01)

Association of 25-hydroxy vitamin D with asthma and its severity in children: a case–control study
by: Alireza Sharif, et al.
Published: (2020-05-01)

Obesity and severe asthma
by: Hiroki Tashiro, et al.
Published: (2019-04-01)

Severe asthma in Japan
by: Hiroyuki Nagase
Published: (2019-04-01)

Severe Eosinophilic Asthma
by: Agamemnon Bakakos, et al.
Published: (2019-09-01)

Asthma heterogeneity and severity
by: Tara F. Carr, et al.
Published: (2016-01-01)

SEVERE ASTHMA IN CHILDREN
by: T R Stroikova, et al.
Published: (2018-12-01)

The Danish severe asthma register: an electronic platform for severe asthma management and research
by: Susanne Hansen, et al.
Published: (2021-01-01)

Blood Neutrophil-to-Lymphocyte Ratio and Urine IL-8 Levels Predict the Type of Bacterial Urinary Tract Infection in Type 2 Diabetes Mellitus Patients
by: Saheb Sharif-Askari F, et al.
Published: (2020-06-01)

Demographic and clinical patterns of severe asthma in the Middle East
by: Mohamed Abuzakouk, et al.
Published: (2021-01-01)

Effect of asthma severity on symptom perception in childhood asthma
by: A.L.B. Cabral, et al.
Published: (2002-03-01)

SANI-Severe Asthma Network in Italy: a way forward to monitor severe asthma
by: G. Senna, et al.
Published: (2017-04-01)

Altered respiratory microbiota composition and functionality associated with asthma early in life
by: Mohammad T. AL Bataineh, et al.
Published: (2020-09-01)

Biological therapy for severe asthma
by: Silvano Dragonieri, et al.
Published: (2021-08-01)

Biological treatments for severe asthma
by: Hyun Jung Jin
Published: (2020-10-01)