Phenotypic and Proteomic Analysis of the Aspergillus fumigatus ΔPrtT, ΔXprG and ΔXprG/ΔPrtT Protease-Deficient Mutants

Phenotypic and Proteomic Analysis of the Aspergillus fumigatus ΔPrtT, ΔXprG and ΔXprG/ΔPrtT Protease-Deficient Mutants

Aspergillus fumigatus is the most common mold species to cause disease in immunocompromised patients. Infection usually begins when its spores (conidia) are inhaled into the airways, where they germinate, forming hyphae that penetrate and destroy the lungs and disseminate to other organs, leading to...

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Bibliographic Details
Main Authors: Einav Shemesh, Benjamin Hanf, Shelly Hagag, Shani Attias, Yana Shadkchan, Boris Fichtman, Amnon Harel, Thomas Krüger, Axel A. Brakhage, Olaf Kniemeyer, Nir Osherov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Microbiology
Subjects:
Aspergillus fumigatus
protease secretion
transcription factor
proteomics
virulence
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02490/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02490/full

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