Resistance to HER2-targeted therapy

Production and approval of trastuzumab (Herceptin®) for the treatment of metastatic breast cancer (MBC) was a millstone in antibody-based targeted therapy in the cancer treatment. However, despite the early success in the clinical trials, trastuzumab failed to appreciate the initial attraction due t...

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Bibliographic Details
Main Authors: Reza Valadan, Alireza Rafiei, Mohsen Tehrani, Forough Nejatollahi
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences and Health Services 2013-02-01
Series:Research in Molecular Medicine
Subjects:
Online Access:http://rmm.mazums.ac.ir/browse.php?a_code=A-10-589-1&slc_lang=en&sid=1