Cryo-electron tomography reveals novel features of a viral RNA replication compartment

Positive-strand RNA viruses, the largest genetic class of viruses, include numerous important pathogens such as Zika virus. These viruses replicate their RNA genomes in novel, membrane-bounded mini-organelles, but the organization of viral proteins and RNAs in these compartments has been largely unk...

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Bibliographic Details
Main Authors: Kenneth J Ertel, Desirée Benefield, Daniel Castaño-Diez, Janice G Pennington, Mark Horswill, Johan A den Boon, Marisa S Otegui, Paul Ahlquist
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/25940