The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study.

The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study.

INTRODUCTION:Murine studies have shown that apolipoprotein E modulates pulmonary function during development, aging, and allergen-induced airway disease. It is not known whether the polymorphic human APOE gene influences pulmonary function. OBJECTIVES:We assessed whether an association exists betwee...

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Main Authors: Alexander M Kulminski, Amisha V Barochia, Yury Loika, Nalini Raghavachari, Konstantin G Arbeev, Mary K Wojczynski, Bharat Thyagarajan, Badri N Vardarajan, Kaare Christensen, Anatoliy I Yashin, Stewart J Levine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6226172?pdf=render

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