The candidate TB vaccine, MVA85A, induces highly durable Th1 responses.

Vaccination against tuberculosis (TB) should provide long-term protective immunity against Mycobacterium tuberculosis (M.tb). The current TB vaccine, Bacille Calmette-Guerin (BCG), protects against disseminated childhood TB, but protection against lung TB in adolescents and adults is variable and mo...

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Bibliographic Details
Main Authors: Michele Tameris, Hennie Geldenhuys, Angelique KanyKany Luabeya, Erica Smit, Jane E Hughes, Samantha Vermaak, Willem A Hanekom, Mark Hatherill, Hassan Mahomed, Helen McShane, Thomas J Scriba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3911992?pdf=render