In vitro–in vivo evaluation of poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) hydrogel implants containing cisplatin

The aim of this study was to prepare hydrogel disc implants containing cisplatin from hydroxyethyl methacrylate (HEMA) and methyl methacrylate (MMA). To control drug release, the monomers were cross-linked with ethyleneglycol dimethacrylate (EGDMA). Implants were characterized by FTIR, DSC and SEM a...

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Bibliographic Details
Main Authors: Madhu Babu, Hemant K.S. Yadav, Afrasim Moin, Hosakote G. Shivakumar
Format: Article
Language:English
Published: Elsevier 2011-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383511000803