Prebiotic Peptide Bond Formation Through Amino Acid Phosphorylation. Insights from Quantum Chemical Simulations

Condensation reactions between biomolecular building blocks are the main synthetic channels to build biopolymers. However, under highly diluted prebiotic conditions, condensations are thermodynamically hampered since they release water. Moreover, these reactions are also kinetically hindered as, in...

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Bibliographic Details
Main Authors: Berta Martínez-Bachs, Albert Rimola
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/9/3/75