ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections.

Genomic tools have revealed genetically diverse pathogens within some hosts. Within-host pathogen diversity, which we refer to as "complex infection", is increasingly recognized as a determinant of treatment outcome for infections like tuberculosis. Complex infection arises through two mec...

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Bibliographic Details
Main Authors: Leonid Chindelevitch, Caroline Colijn, Prashini Moodley, Douglas Wilson, Ted Cohen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4734664?pdf=render