Signaling flux redistribution at toll-like receptor pathway junctions.

Various receptors on cell surface recognize specific extracellular molecules and trigger signal transduction altering gene expression in the nucleus. Gain or loss-of-function mutations of one molecule have shown to affect alternative signaling pathways with a poorly understood mechanism. In Toll-lik...

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Bibliographic Details
Main Authors: Kumar Selvarajoo, Yasunari Takada, Jin Gohda, Mohamed Helmy, Shizuo Akira, Masaru Tomita, Masa Tsuchiya, Jun-Ichiro Inoue, Koichi Matsuo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2561291?pdf=render