Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention

Thiazolidinediones (TZDs) are one of the major classes of antidiabetic drugs that are used widely. TZDs improve insulin resistance by activating peroxisome proliferator-activated receptor gamma (PPARγ) and ameliorate diabetic and other nephropathies, at least, in experimental animals. However, TZDs...

Full description

Bibliographic Details
Main Authors: Shoko Horita, Motonobu Nakamura, Nobuhiko Satoh, Masashi Suzuki, George Seki
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2015/646423