Molecular characterization and cell type composition deconvolution of fibrosis in NAFLD

Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. In adults with NAFLD, fibrosis can develop and progress to liver cirrhosis and liver failure. However, the underlying molecular mechanisms of fibrosis progression are not fully understood. Using t...

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Bibliographic Details
Main Authors: Lorena Pantano, George Agyapong, Yang Shen, Zhu Zhuo, Francesc Fernandez-Albert, Werner Rust, Dagmar Knebel, Jon Hill, Carine M. Boustany-Kari, Julia F. Doerner, Jörg F. Rippmann, Raymond T. Chung, Shannan J. Ho Sui, Eric Simon, Kathleen E. Corey
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96966-5