Pfcrt haplotypes and the evolutionary history of chloroquine-resistant Plasmodium falciparum

Mutations in the Pfcrt gene that change the resulting amino acids and form different haplotypes are common and correlate with the prevalence of chloroquine resistant (CQR) field isolates of the malaria parasite, Plasmodium falciparum. This correlation provides opportunities to infer the global evolu...

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Bibliographic Details
Main Authors: Gauri Awasthi, Godavarthi Bhogendra Krishna Satya, Aparup Das
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2012-02-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000100018&lng=en&tlng=en