Childhood Adversity Is Associated With Increased KITLG Methylation in Healthy Individuals but Not in Bipolar Disorder Patients

Childhood Adversity Is Associated With Increased KITLG Methylation in Healthy Individuals but Not in Bipolar Disorder Patients

Background: Childhood adversity increases the risk of a range of mental disorders including bipolar disorder, but the underlying mechanisms are still unknown. Previous studies identified DNA methylation levels at the cg27512205 locus on the KIT Ligand (KITLG) gene as a mediator between childhood adv...

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Bibliographic Details
Main Authors: Yujie He, Christiaan H. Vinkers, Lotte C. Houtepen, Lot D. de Witte, Marco P. Boks
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Psychiatry
Subjects:
DNA methylation
KITLG
bipolar disorder
childhood adversity
stress
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00743/full

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https://www.frontiersin.org/article/10.3389/fpsyt.2018.00743/full

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