A Short-Term Exposure to Tributyltin Blocks Leydig Cell Regeneration in the Adult Rat Testis

Background: Tributyltin (TBT) is widely used as an antifouling agent that may cause reproductive toxicity. The mechanism of TBT on Leydig cell development is still unknown. The objective of the present study was to investigate whether a brief exposure to low doses of TBT permanently affects Leydig c...

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Bibliographic Details
Main Authors: Xiaolong Wu, Jianpeng Liu, Yue Duan, Shiyu Gao, Yao Lü, Xiaoheng Li, Qiqi Zhu, Xianwu Chen, Jing Lin, Leping Ye, Ren-Shan Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00704/full