Elevated Neurofilament Light Chain in Cerebrospinal Fluid and Plasma Reflect Inflammatory MRI Activity in Neurosarcoidosis

Elevated Neurofilament Light Chain in Cerebrospinal Fluid and Plasma Reflect Inflammatory MRI Activity in Neurosarcoidosis

Background: Damage to axonal cells releases neurofilament light chain (NFL) into the cerebrospinal fluid and plasma. The objective of this study was to investigate NFL as a potential biomarker of disease activity in neurosarcoidosis. MRIs were graded according to enhancing lesions at different centr...

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Bibliographic Details
Main Authors: Keld-Erik Byg, Helle H. Nielsen, Tobias Sejbaek, Jonna Skov Madsen, Dorte Aalund Olsen, Nina Nguyen, Astrid Kindt, Jakob Grauslund, Zsolt Illes, Torkell Ellingsen
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Brain Sciences
Subjects:
neurofilament light chain
biomarker
neurosarcoidosis
cerebrospinal fluid
MRI
Online Access:https://www.mdpi.com/2076-3425/11/2/238

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