Sonic hedgehog promotes autophagy in hippocampal neurons

Summary The Sonic hedgehog (Shh) signaling pathway is well known in patterning of the neural tube during embryonic development, but its emerging role in differentiated neurons is less understood. Here we report that Shh enhances autophagy in cultured hippocampal neurons. Microarray analysis reveals...

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Bibliographic Details
Main Authors: Ronald S. Petralia, Catherine M. Schwartz, Ya-Xian Wang, Elisa M. Kawamoto, Mark P. Mattson, Pamela J. Yao
Format: Article
Language:English
Published: The Company of Biologists 2013-04-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/5/499