The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus.

The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus.

Efficient adaptation to iron starvation is an essential virulence determinant of the most common human mold pathogen, Aspergillus fumigatus. Here, we demonstrate that the cytosolic monothiol glutaredoxin GrxD plays an essential role in iron sensing in this fungus. Our studies revealed that (i) GrxD...

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Bibliographic Details
Main Authors: Matthias Misslinger, Mareike Thea Scheven, Peter Hortschansky, Manuel Sánchez López-Berges, Katharina Heiss, Nicola Beckmann, Thomas Heigl, Martin Hermann, Thomas Krüger, Olaf Kniemeyer, Axel A Brakhage, Hubertus Haas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008379

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https://doi.org/10.1371/journal.pgen.1008379

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