Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer

Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer

IntroductionDysregulation of NLRP3 inflammasome complex formation can promote chronic inflammation by increased release of IL-1β. However, the effect of NLRP3 complex formation on tumor progression remains controversial. Therefore, we sought to determine the effect of NLRP3 modulation on the growth...

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Bibliographic Details
Main Authors: Gulcin Tezcan, Ekaterina E. Garanina, Mohammad Alsaadi, Zarema E. Gilazieva, Ekaterina V. Martinova, Maria I. Markelova, Svetlana S. Arkhipova, Shaimaa Hamza, Alan McIntyre, Albert A. Rizvanov, Svetlana F. Khaiboullina
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
NLRP3
inflammasome
cancer
IL-1β
nigericin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.607881/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.607881/full

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