Mitochondrial respiratory capacity modulates LPS-induced inflammatory signatures in human blood

Mitochondria modulate inflammatory processes in various model organisms, but it is unclear how much mitochondria regulate immune responses in human blood leukocytes. Here, we examine the effect of i) experimental perturbations of mitochondrial respiratory chain function, and ii) baseline inter-indiv...

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Bibliographic Details
Main Authors: Kalpita Rashmi Karan, Caroline Trumpff, Marlon A. McGill, Jacob E. Thomas, Gabriel Sturm, Vincenzo Lauriola, Richard P. Sloan, Nicolas Rohleder, Brett A. Kaufman, Anna L. Marsland, Martin Picard
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
LPS
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354620300454