Internalization dissociates β2-adrenergic receptors.

G protein-coupled receptors (GPCRs) self-associate as dimers or higher-order oligomers in living cells. The stability of associated GPCRs has not been extensively studied, but it is generally thought that these receptors move between the plasma membrane and intracellular compartments as intact dimer...

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Bibliographic Details
Main Authors: Tien-Hung Lan, Sudhakiranmayi Kuravi, Nevin A Lambert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3043075?pdf=render