Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells.
Hematopoietic stem cells (HSC) are rare, multipotent cells capable of generating all specialized cells of the blood system. Appropriate regulation of HSC quiescence is thought to be crucial to maintain their lifelong function; however, the molecular pathways controlling stem cell quiescence remain p...
Main Authors: | E Camilla Forsberg, Emmanuelle Passegué, Susan S Prohaska, Amy J Wagers, Martina Koeva, Joshua M Stuart, Irving L Weissman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2808351?pdf=render |
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