Collagen VI Null Mice as a Model for Early Onset Muscle Decline in Aging

Collagen VI Null Mice as a Model for Early Onset Muscle Decline in Aging

Collagen VI is an extracellular matrix (ECM) protein playing a key role in skeletal muscles and whose deficiency leads to connective tissue diseases in humans and in animal models. However, most studies have been focused on skeletal muscle features. We performed an extensive proteomic profiling in t...

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Bibliographic Details
Main Authors: Daniele Capitanio, Manuela Moriggi, Sara De Palma, Dario Bizzotto, Sibilla Molon, Enrica Torretta, Chiara Fania, Paolo Bonaldo, Cecilia Gelfi, Paola Braghetta
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
collagen VI
aging muscle proteome
skeletal muscle
autophagy
lipotoxicity
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00337/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00337/full

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